Researchers Identify Gene Variant Linked to Glaucoma

A team of researchers has recently discovered gene variants linked to glaucoma. The findings of this research could pave the way for future treatments and possibly even a cure for the disease.

The study examined patients from the Afro-Caribbean population of Barbados; approximately 10% of this population suffers from glaucoma, nearly twice the figure in other regions. This sample group was chosen due to their strong genetic predisposition to the disease.

The study identified a gene variant, present in 40% of the individuals with glaucoma in Barbados, which explains close to one third of their genetic risk for the disease. This study should enable researchers to develop gene or stem-cell based therapies to treat glaucoma. Identifying gene variants can also lead to a more accurate and earlier diagnosis, which would help slow the progression of the disorder in patients while a cure is being developed.

Glaucoma currently causes blindness in more than two million Americans each year. The disease results in the death of ganglion cells in the retina. Over time, patients with glaucoma suffer a gradual and permanent loss of peripheral vision. The progression of the disease can be slowed by reducing intra-ocular pressure, but currently there is no known cure. Hopefully, this study can drastically improve the ability to treat and even cure glaucoma.